133745-75-2 Usage
Chemical Properties
Off-white to light brown crystalline powder
Uses
Different sources of media describe the Uses of 133745-75-2 differently. You can refer to the following data:
1. Versatile fluorinating reagent used in the fluorination of aryls, enolates, carbanions, organolithiums, etc.
2. N-Fluorobenzenesulfonimide fluorinates aromatics, enolates, azaenolates and carbanions in high yield. It is used for diastereoselective fluorination of Li enolates of chiral carboximides, for directed fluorination of ortho-lithiated aromatics and for a review of electrophilic N-F fluorinating agents. Asymmteric fluorinations is effected in the presence of a Pd-BINAP catalyst system at room temperature in an ionic liquid. It is a reagent employed in a palladium-catalyzed enantioselective fluorination of t-butoxycarbonyl lactones and lactams. It is also used in the electrophilic difluorination of dihalopyridines with butyl lithium and in the direct conversion of alcohols to dibenzenesulfonamides with triphenylphosphine.
General Description
N-Fluorobenzenesulfonimide (NFSi) is a commonly used electrophilic fluorinating agent in organic synthesis to introduce fluorine into neutral organic molecules. It is also used to fluorinate nucleophilic substrates such as reactive organometallic species and malonate anions.NFSi can be synthesized by the reaction of benzenesulfonimide with fluorine.
Check Digit Verification of cas no
The CAS Registry Mumber 133745-75-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,7,4 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 133745-75:
(8*1)+(7*3)+(6*3)+(5*7)+(4*4)+(3*5)+(2*7)+(1*5)=132
132 % 10 = 2
So 133745-75-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H4F6O2/c10-8(11,12)5-2-1-4(7(16)17)3-6(5)9(13,14)15/h1-3H,(H,16,17)
133745-75-2Relevant articles and documents
Comparative studies on the enantioselective fluorination of oxindoles with structurally modified N-fluorobenzenesulfonimides
Zhang, Yan,Yang, Xian-Jin,Xie, Tian,Chen, Guan-Long,Zhu, Wen-Hua,Zhang, Xiao-Qi,Yang, Xue-Yan,Wu, Xin-Yan,He, Xiao-Peng,He, Hao-Ming
, p. 4933 - 4937 (2013/07/25)
Structurally modified N-fluorobenzenesulfonimides (NFSIs) have been used to study the enantioselective fluorination of oxindoles in the presence of a bis-cinchona alkaloid, (DHQD)2PHAL, as the catalyst. We observe that the NFSI analogues bearin
Method for preparing N-fluorosulfonimides
-
, (2008/06/13)
The present invention relates to a process of preparing N-benzenesulfonimides comprising reacting an alkali metal salt of a sulfonimide with fluorine in the presence of water or water/organic solvent mixtures. N-fluorosulfonimides are useful as fluorinati
