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1361253-21-5

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1361253-21-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1361253-21-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,1,2,5 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1361253-21:
(9*1)+(8*3)+(7*6)+(6*1)+(5*2)+(4*5)+(3*3)+(2*2)+(1*1)=125
125 % 10 = 5
So 1361253-21-5 is a valid CAS Registry Number.

1361253-21-5Relevant articles and documents

Optimization of hydroxybenzothiazoles as novel potent and selective inhibitors of 17β-HSD1

Spadaro, Alessandro,Frotscher, Martin,Hartmann, Rolf W.

supporting information; experimental part, p. 2469 - 2473 (2012/05/20)

17β-HSD1 is a novel target for the treatment of estrogen-dependent diseases, as it catalyzes intracellular estradiol formation. Starting from two recently described compounds, highly active and selective inhibitors were developed. Benzoyl 6 and benzamide 17 are the most selective compounds toward 17β-HSD2 described so far. They also showed a promising profile regarding activity in T47-D cells, selectivity toward ERα and ERβ, inhibition of hepatic CYP enzymes, metabolic stability, and inhibition of marmoset 17β-HSD1 and 17β-HSD2.

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