87808-44-4Relevant academic research and scientific papers
DOPAMINE RECEPTOR D1 AGONISTS AND METHODS OF USE
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Paragraph 00198-00199, (2021/02/05)
Described herein are small molecule agonists of dopamine receptor D1 that inhibit YAP/TAZ, compositions, and methods of using these compounds and compositions.
Synthesis method of 2-methoxyl-4-cyanobenzaldehyde
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Paragraph 0038; 0039; 0052; 0064; 0076, (2018/04/03)
The invention discloses a synthesis method of 2-methoxyl-4-cyanobenzaldehyde. The method comprises the following steps: 1, carrying out acylating chlorination on 4-methyl-3-methoxybenzoic acid servingas a raw material, and then carrying out aminolysis to
Discovery of novel modulators of metabotropic glutamate receptor subtype-5
Wang, Bowei,Vernier, Jean-Michel,Rao, Sara,Chung, Janice,Anderson, Jeffery J.,Brodkin, Jesse D.,Jiang, Xiaohui,Gardner, Michael F.,Yang, Xiaoqing,Munoz, Benito
, p. 17 - 21 (2007/10/03)
A series of potent and selective mGluR5 antagonists were synthesized and evaluated in vitro and in vivo. It was found that a pyridyl functionality is a potential replacement for acetonitrile in the lead structure, with 2-pyridyl being most favored. Additi
Pharmaceutically active phenylcarboxylic acid derivatives
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, (2008/06/13)
Compounds which antagonize the slow-reacting substance of anaphylaxis or components thereof, e.g., leukotrienes, in warm blooded animals as well as intermediates and methods for their preparation, pharmaceutical compositions and methods for their administration. The compounds are diphenyl carboxylic acids with particular linking groups between the individual phenyl rings and the carboxylic acid moiety. Particular utilities are to relieve asthma and inflammation in man.
