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CAS

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1361253-26-0

2,4-difluoro-3-methoxy-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1361253-26-0 Structure

  • Basic information

    1. Product Name: 2,4-difluoro-3-methoxy-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide
    2. Synonyms:
    3. CAS NO:1361253-26-0
    4. Molecular Formula:
    5. Molecular Weight: 350.346
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1361253-26-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,4-difluoro-3-methoxy-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,4-difluoro-3-methoxy-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide(1361253-26-0)
    11. EPA Substance Registry System: 2,4-difluoro-3-methoxy-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide(1361253-26-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1361253-26-0(Hazardous Substances Data)

1361253-26-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1361253-26-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,1,2,5 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1361253-26:
(9*1)+(8*3)+(7*6)+(6*1)+(5*2)+(4*5)+(3*3)+(2*2)+(1*6)=130
130 % 10 = 0
So 1361253-26-0 is a valid CAS Registry Number.

1361253-26-0Relevant articles and documents

Optimization of hydroxybenzothiazoles as novel potent and selective inhibitors of 17β-HSD1

Spadaro, Alessandro,Frotscher, Martin,Hartmann, Rolf W.

supporting information; experimental part, p. 2469 - 2473 (2012/05/20)

17β-HSD1 is a novel target for the treatment of estrogen-dependent diseases, as it catalyzes intracellular estradiol formation. Starting from two recently described compounds, highly active and selective inhibitors were developed. Benzoyl 6 and benzamide 17 are the most selective compounds toward 17β-HSD2 described so far. They also showed a promising profile regarding activity in T47-D cells, selectivity toward ERα and ERβ, inhibition of hepatic CYP enzymes, metabolic stability, and inhibition of marmoset 17β-HSD1 and 17β-HSD2.

SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS

-

Page/Page column 107-108, (2012/03/26)

The invention relates to selective, non-steroidal 17beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitors their production and use, especially for the treatment and/or prophylaxis of hormone-related diseases.

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