1361253-38-4

Basic information

• Product Name: 1-(benzylamino)-1-(2-hydroxyethyl)cyclopentane
• Synonyms: 1-(benzylamino)-1-(2-hydroxyethyl)cyclopentane
• CAS NO: 1361253-38-4
• Molecular Weight: 219.327
• Mol File: 1361253-38-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(benzylamino)-1-(2-hydroxyethyl)cyclopentane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzylamino)-1-(2-hydroxyethyl)cyclopentane(1361253-38-4)
• EPA Substance Registry System: 1-(benzylamino)-1-(2-hydroxyethyl)cyclopentane(1361253-38-4)

Safety Data

• Hazardous Substances Data: 1361253-38-4(Hazardous Substances Data)

Upstream product

• 120-92-3 cyclopentanone 
• 3197-76-0 ethyl 2-(1-hydroxycyclopentyl)acetate 
• 1361253-37-3 ethyl 2-(1-(benzoylamino)cyclopentyl)acetate 

Downstream Products

• 896734-87-5 1-amino-1-(2-hydroxyethyl)cyclopentane 

Relevant articles and documents

Quinolone derivatives containing strained spirocycle as orally active glycogen synthase kinase 3β (GSK-3β) inhibitors for type 2 diabetics

The design, synthesis, and evaluation of 6-6-7 tricyclic quinolones containing the strained spirocycle moiety aiming at the GSK-3β inhibitor were described. Among the synthesized compounds, 44, having a cyclobutane ring on a spirocycle, showed excellent GSK-3β inhibitory activity in both cell-free and cell-based assays (IC50 = 36 nM, EC50 = 3.2 μM, respectively). Additionally, 44 decreased the plasma glucose concentration dose-dependently after an oral glucose tolerance test in mice.