896734-87-5 Usage
Structure
A cyclopentane derivative containing an amino group and a hydroxyethyl group attached to the same carbon atom
Usage
In the synthesis of pharmaceuticals and agrochemicals, and as a chiral auxiliary in asymmetric synthesis
Reactivity
The hydroxyethyl group provides a reactive site for further functionalization, making it a versatile building block for organic chemistry
Value
Its unique structure and properties make it a valuable intermediate in the production of various chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 896734-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,6,7,3 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 896734-87:
(8*8)+(7*9)+(6*6)+(5*7)+(4*3)+(3*4)+(2*8)+(1*7)=245
245 % 10 = 5
So 896734-87-5 is a valid CAS Registry Number.
896734-87-5Relevant articles and documents
Quinolone derivatives containing strained spirocycle as orally active glycogen synthase kinase 3β (GSK-3β) inhibitors for type 2 diabetics
Seto, Shigeki,Yumoto, Kazuhiko,Okada, Kyoko,Asahina, Yoshikazu,Iwane, Aya,Iwago, Maki,Terasawa, Reiko,Shreder, Kevin R.,Murakami, Koji,Kohno, Yasushi
, p. 1188 - 1200 (2012/03/26)
The design, synthesis, and evaluation of 6-6-7 tricyclic quinolones containing the strained spirocycle moiety aiming at the GSK-3β inhibitor were described. Among the synthesized compounds, 44, having a cyclobutane ring on a spirocycle, showed excellent GSK-3β inhibitory activity in both cell-free and cell-based assays (IC50 = 36 nM, EC50 = 3.2 μM, respectively). Additionally, 44 decreased the plasma glucose concentration dose-dependently after an oral glucose tolerance test in mice.
