1361331-91-0Relevant academic research and scientific papers
Total synthesis of a noricumazole A library and evaluation of HCV inhibition
Barbier, Jenny,Wegner, Jens,Benson, Stefan,Gentzsch, Juliane,Pietschmann, Thomas,Kirschning, Andreas
, p. 9083 - 9090 (2012/10/08)
The total synthesis of 16 new ion channel inhibitors derived from noricumazole A, a secondary metabolite from the myxobacterium Sorangium cellulosum, is reported. Particular focus of library design is put on stereochemical permutations in the central regi
Isolation and total synthesis of icumazoles and noricumazoles-antifungal antibiotics and cation-channel blockers from Sorangium cellulosum
Barbier, Jenny,Jansen, Rolf,Irschik, Herbert,Benson, Stefan,Gerth, Klaus,B?hlendorf, Bettina,H?fle, Gerhard,Reichenbach, Hans,Wegner, Jens,Zeilinger, Carsten,Kirschning, Andreas,Müller, Rolf
, p. 1256 - 1260 (2012/03/10)
Joint efforts: The antifungal icumazole A, the potassium-ion-channel inhibitor noricumazole A, and their glycosylated derivatives are new, structurally related secondary metabolites isolated from Sorangium cellulosum. Their structures have been fully assi
