1361332-06-0Relevant academic research and scientific papers
Isolation and total synthesis of icumazoles and noricumazoles-antifungal antibiotics and cation-channel blockers from Sorangium cellulosum
Barbier, Jenny,Jansen, Rolf,Irschik, Herbert,Benson, Stefan,Gerth, Klaus,B?hlendorf, Bettina,H?fle, Gerhard,Reichenbach, Hans,Wegner, Jens,Zeilinger, Carsten,Kirschning, Andreas,Müller, Rolf
, p. 1256 - 1260 (2012/03/10)
Joint efforts: The antifungal icumazole A, the potassium-ion-channel inhibitor noricumazole A, and their glycosylated derivatives are new, structurally related secondary metabolites isolated from Sorangium cellulosum. Their structures have been fully assi
Total synthesis of a noricumazole A library and evaluation of HCV inhibition
Barbier, Jenny,Wegner, Jens,Benson, Stefan,Gentzsch, Juliane,Pietschmann, Thomas,Kirschning, Andreas
, p. 9083 - 9090 (2012/10/08)
The total synthesis of 16 new ion channel inhibitors derived from noricumazole A, a secondary metabolite from the myxobacterium Sorangium cellulosum, is reported. Particular focus of library design is put on stereochemical permutations in the central regi
