136138-26-6

Usage

Uses

Used in Pharmaceutical Research:
N-(2-iodophenyl)-2-methoxybenzamide is used as a research compound for the development of new pharmaceuticals. Its unique structure and properties make it a promising candidate for drug discovery and design.
Used in Organic Synthesis:
N-(2-iodophenyl)-2-methoxybenzamide is used as a building block in the synthesis of complex organic molecules. Its versatility and reactivity make it a valuable component in the creation of new compounds.
Used in PET Imaging:
N-(2-iodophenyl)-2-methoxybenzamide may be used as a radioligand in Positron Emission Tomography (PET) imaging. Its iodine content and chemical structure make it a potential candidate for use in diagnostic imaging applications.
Used in Drug Development:
N-(2-iodophenyl)-2-methoxybenzamide is used as a precursor in the synthesis of novel pharmaceuticals. Its unique properties and potential bioactivity make it a valuable starting point for the development of new drugs.

Upstream product

• 615-43-0 2-iodophenylamine 
• 529-28-2 4-iodoanisol 
• 21615-34-9 2-Methoxybenzoyl chloride 

Downstream Products

• 1103883-08-4 C₁₉H₂₀INO₄ 
• 60681-96-1 2-(2-methoxyphenyl)-4H-benzo[d][1,3]oxazin-4-one 
• 934668-60-7 N-(2-(4-nitrophenylthio)phenyl)-2-methoxybenzamide 
• 1391741-31-3 N-(2-(4-aminophenylthio)phenyl)-2-methoxybenzamide 
• 13459-17-1 2-(2-methoxyphenyl)-1,3-benzoxazole 
• 136138-44-8 [2-(2-Methoxy-benzoyl)-phenyl]-carbamic acid ethyl ester 

Relevant academic research and scientific papers

Dibrominative Spirocyclization of 2-Butynolyl Anilides: Synthesis of gem-Dibromospirocyclic Benzo[ d][1,3]oxazines and Their Application in the Synthesis of 4 H-Furo[3,2- b]indoles

The combination of catalytic aqueous hydrochloric acid (HCl) and N-bromosuccinimide (NBS) generated electrophilic bromine monochloride (BrCl), which readily induced spiroannulation of 2-alkynolyl anilides (n = 1-3) to form gem-dibromospirocyclic benzo[d][

A flexible approach to Pd-catalyzed carbonylations via aroyl dimethylaminopyridinium salts

4-Dimethylaminopyridine (DMAP) is shown to undergo Pd/PtBu3 catalyzed coupling with aryl halides and carbon monoxide to form electrophilic aroyl-DMAP salts. The reaction is easily scalable to prepare multigram quantities with low catalyst loadings, while the precipitation of these salts as they form leads to products with low impurities. These reagents rapidly react with a variety of nucleophiles, including those that contain potentially incompatible functional groups under standard carbonylative conditions.

Intermolecular coupling of 2-iodoanilides with benzoxazoles: Synthesis of N-(2-Benzoxazol-2-ylphenyl)benzamides via C-H activation

Using CuI/xantphos/Pd(OAc)2 catalytic system, the intermolecular C-C cross coupling between benzoxazoles and ortho-haloanilides has been developed in moderate to good yields. The procedure tolerates a series of functional groups on benzoxazole, such as ester, chloro, methyl, and methoxy groups. This divergent approach provides access to various N-(2-Benzoxazol-2-ylphenyl)amides.