1361388-76-2

Upstream product

• 10272-07-8 3.5-dimethoxyaniline 
• 123-11-5 4-methoxy-benzaldehyde 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 1361388-79-5 C₂₀H₂₁NO₆ 
• 1361388-59-1 4-methoxybenzylidene-(3,5-dimethoxyphenyl)amine 

Downstream Products

• 1361388-55-7 (-)-3,4-trans-1-(3,5-dimethoxyphenyl)-3-hydroxy-4-(4-methoxyphenyl)azetidin-2-one 

Relevant academic research and scientific papers

1,4-DIARYL-2-AZETIDINONES WITH ANTI-TUMORAL ACTIVITY

Disclosed are compounds of formula (I): wherein one of A and B is the group:(II) wherein R1 is selected from H and OCH3, and the other is the group:(III) wherein R2 is selected from H, OH, NO2, NH2; R

Synthesis and biological evaluation of 1,4-diaryl-2-azetidinones as specific anticancer agents: Activation of adenosine monophosphate activated protein kinase and induction of apoptosis

A series of novel 1,4-diaryl-2-azetidinones were synthesized and evaluated for antiproliferative activity, cell cycle effects, and apoptosis induction. Strong cytotoxicity was observed with the best compounds (±)-trans-20, (±)-trans-21, and enantiomers (+