1361388-77-3

Upstream product

• 621-59-0 isovanillin 
• 1261242-75-4 2‐methoxy‐5‐[(3,4,5‐trimethoxyphenylimino)methyl]phenol 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 24313-88-0 3,4,5-Trimethoxyaniline 

Downstream Products

• 1361388-57-9 (+)-3,4-trans-3-hydroxy-4-(3-hydroxy-4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)azetidin-2-one 

Relevant academic research and scientific papers

1,4-DIARYL-2-AZETIDINONES WITH ANTI-TUMORAL ACTIVITY

Disclosed are compounds of formula (I): wherein one of A and B is the group:(II) wherein R1 is selected from H and OCH3, and the other is the group:(III) wherein R2 is selected from H, OH, NO2, NH2; R

Synthesis and biological evaluation of 1,4-diaryl-2-azetidinones as specific anticancer agents: Activation of adenosine monophosphate activated protein kinase and induction of apoptosis

A series of novel 1,4-diaryl-2-azetidinones were synthesized and evaluated for antiproliferative activity, cell cycle effects, and apoptosis induction. Strong cytotoxicity was observed with the best compounds (±)-trans-20, (±)-trans-21, and enantiomers (+