1361405-58-4Relevant academic research and scientific papers
Synthesis, characterization, and herbicidal activities of new 1,3,4-oxadiazoles, 1,3,4-thiadiazoles, and 1,2,4-triazoles derivatives bearing (r)-5-chloro-3-fluoro-2-phenoxypyridine
Kalhor, Mehdi,Dadras, Akbar
, p. 220 - 224 (2013)
Synthesis of some novel 1,2,4-triazoles, 1,3,4-oxadiazoles and 1,3,4-thiadiazoles bearing a (R) 5-(1-(4-(5-chloro-3-fluoropyridin-2-yloxy) phenoxy)ethyl) unit, as a moiety of commercial herbicide, using their thiosemicarbazides in an alkaline, iodine and acidic media is reported, respectively. The structure of the synthesized compounds was characterized by IR, 1H, 13C NMR spectroscopic data, and elemental analyses. The herbicidal activities of synthesized compounds were evaluated against Echinochloa cruss-galli, Avena fatua, and Sorgum halepense weeds. Compounds 7 and 12a showed potential herbicidal activity against gramineous weeds. Our results may provide some guidance for synthesis development of some novel oxa or thiadiazole and triazole-based herbicidal lead structures.
A new method for one-pot synthesis of aryloxyphenoxypropionate herbicides using 2,4,6-trichloro-1,3,5-triazine and (n-BU)4NI as a homogeneous catalyst
Kalhor, Mehdi,Dadras, Akbar,Mobinikhaledi, Akbar,Tajik, Hassan
experimental part, p. 833 - 836 (2012/05/04)
The one-pot reaction of halo-heterocycle, (R)-4-hydroxyphenoxy propionic acid and an alcohol, amine or sulfonamide is described as an efficient method for the synthesis of aryloxyphenoxy propionate hrerbicides by using 2,4,6-trichloro-1,3,5-triazine in the presence of (n-BU) 4NI, as a homogeneous catalyst under mild conditions. The present procedure offers several advantages, such as good yields, short reaction times and easy workup.
