(R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide

Base Information

Chemical Name:(R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide
CAS No.:1361405-58-4
Molecular Formula:C₁₄H₁₃ClFN₃O₃
Molecular Weight:325.727
Hs Code.:

Synonyms:(R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide

Suppliers and Price of (R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide

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Technology Process of (R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide

There total 2 articles about (R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 105512-06-9
2-propynyl (R)-2-[4-(5-chloro-3-fluoro-2-pyridinyloxy)-phenoxy]-propionate

: 1361405-58-4
(R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide

Guidance literature:: With hydrazine hydrate; In methanol; for 0.25h; Reflux;
DOI:10.1002/jhet.950

Reference yield: 87.0%

: 89402-43-7
5-chloro-2,3-difluoropyridine

: 94050-90-5
(R)-2-(4-hydroxyphenoxy)propionic acid

: 302-01-2,78206-91-4,119775-10-9,75013-58-0
hydrazine

: 1361405-58-4
(R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy]propionic acid hydrazide

Guidance literature:: 5-chloro-2,3-difluoropyridine; (R)-2-(4-hydroxyphenoxy)propionic acid; With potassium phosphate; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 50 - 60 ℃; for 2h;

With 1,3,5-trichloro-2,4,6-triazine; In N,N-dimethyl-formamide; at 5 - 25 ℃; for 1.16667h;

hydrazine; In N,N-dimethyl-formamide;
DOI:10.4067/S0717-97072011000400002