1361410-57-2Relevant articles and documents
One-pot preparation of piperazines by regioselective ring-opening of non-activated arylaziridines
Trinchera, Piera,Musio, Biagia,Degennaro, Leonardo,Moliterni, Anna,Falcicchio, Aurelia,Luisi, Renzo
supporting information; experimental part, p. 1962 - 1965 (2012/04/23)
Herein we report a new straightforward synthesis of cis and trans 2,5-disubstituted N,N-dialkylpiperazines, even in enantioenriched form, by reacting non-activated N-alkyl arylaziridines in the presence of a catalytic amount of a Lewis acid. A stereochemi