1361411-97-3Relevant academic research and scientific papers
The synthesis of α-aryl-α-aminophosphonates and α-aryl-α-aminophosphine oxides by the microwave-assisted Pudovik reaction
Bálint, Erika,Tajti, ádám,ádám, Anna,Csontos, István,Karaghiosoff, Konstantin,Czugler, Mátyás,ábrányi-Balogh, Péter,Keglevich, Gy?rgy
, p. 76 - 86 (2017)
A family of α-aryl-α-aminophosphonates and α-aryl-α-aminophosphine oxides was synthesized by the microwave-assisted solvent-free addition of dialkyl phosphites and diphenylphosphine oxide, respectively, to imines formed from benzaldehyde derivatives and primary amines. After optimization, the reactivity was mapped, and the fine mechanism was evaluated by DFT calculations. Two α-aminophosphonates were subjected to an X-ray study revealing a racemic dimer formation made through a N-H?O=P intermolecular hydrogen bridges pair.
Synthesis of α-aminophosphonates from α-hydroxyphosphonates; a theoretical study
Kiss, Nóra Zsuzsa,Rádai, Zita,Mucsi, Zoltán,Keglevich, Gy?rgy
, p. 260 - 268 (2016/10/11)
Two types of reactions, namely the Pudovik reaction of benzaldehyde and acetophenone with diethyl phosphite as well as the substitution of the α-hydroxyphosphonates so-formed by primary amines to afford α-aminophosphonates, were evaluated by quantum chemi
