1361465-94-2Relevant academic research and scientific papers
Efficient and connective assembly of highly functionalized benzofurans using o-hydroxyphenones and dichloroethylene
Schevenels, Florian,Marko, Istvan E.
, p. 1298 - 1301 (2012)
The preparation of highly functionalized benzofurans by a unique and connective transformation is reported. Base-catalyzed condensation of o-hydroxyphenones with 1,1-dichloroethylene generates the corresponding chloromethylene furans. These labile intermediates undergo a facile rearrangement into benzofuran carbaldehydes under mild acidic conditions.
