136166-36-4

Basic information

• Product Name: Sulfamic acid, ethyl-, 1-[(2-methoxyphenoxy)methyl]-1,2-ethanediyl ester
• CAS NO: 136166-36-4
• Molecular Formula: C14H24N2O8S2
• Molecular Weight: 412.485
• Mol File: 136166-36-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Sulfamic acid, ethyl-, 1-[(2-methoxyphenoxy)methyl]-1,2-ethanediyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Sulfamic acid, ethyl-, 1-[(2-methoxyphenoxy)methyl]-1,2-ethanediyl ester(136166-36-4)
• EPA Substance Registry System: Sulfamic acid, ethyl-, 1-[(2-methoxyphenoxy)methyl]-1,2-ethanediyl ester(136166-36-4)

Safety Data

• Hazardous Substances Data: 136166-36-4(Hazardous Substances Data)

Upstream product

• 16548-07-5 ethylsulfamoyl chloride 
• 93-14-1 guaifenesin 

Relevant articles and documents

Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals

Methods of treating chronic arthritis and osteoporosis which utilize both known and novel compounds which would fall under the general formula:(HO)p--A--[--OS(O) 2 NR 1 R 2 ] zwherein A encompasses a wide range of values including but not limited to aryl, loweralkyl, cycloalkyl, and carbohydrates including sucrose and fructose; p is equal to the number of unreacted hydroxy groups contained on the molecule and may be zero; z is the number of --OS(O) 2 NR 1 R 2 groups and is always at least one; R 1 and R 2 are selected from hydrogen, loweralkyl, carboxy and the like; a novel process for preparing the compounds is provided wherein an appropriate sulfamic acid aryl ester is reacted with a hydroxy substituted A radical which may or may not contain thereon protected carboxyl, amino or hydroxy substituents, in an aprotic solvent containing a tertiary amine base. Pharmaceutical compositions for the treatment of chronic arthritis and osteoporosis are also provided.