1361843-97-1Relevant academic research and scientific papers
(Diacyloxyiodo)benzenes-Driven Palladium-Catalyzed Cyclizations of Unsaturated N-Sulfonylamides: Opportunities of Path Selection
Borelli, Tea,Brenna, Stefano,Broggini, Gianluigi,Oble, Julie,Poli, Giovanni
, p. 623 - 628 (2017)
A study of the palladium(II)-catalyzed cyclization of unsaturated N-sulfonylamides was undertaken, using (diacyloxyiodo)benzenes as terminal oxidizing agents. Different reactivities were observed as a function of the nature of the unsaturation (terminal vs. internal), or of the hypervalent iodine compound used (diacetoxyiodobenzene vs. bistrifluoroacetoxyiodobenzene). Proper parameter selection allows the direction of the cyclization to be chosen towards either a global aminoacetoxylation, an allylic amination via aminopalladation, or an allylic amination via allylic C–H activation. (Figure presented.).
Intramolecular Pd(II)-catalyzed aerobic oxidative amination of alkenes: Synthesis of six-membered N-heterocycles
Lu, Zhan,Stahl, Shannon S.
supporting information; experimental part, p. 1234 - 1237 (2012/04/18)
Use of a base-free Pd(DMSO)2(TFA)2 catalyst system enables the synthesis of six-membered nitrogen heterocycles via a Wacker-type aerobic oxidative cyclization of alkenes bearing tethered sulfonamides. Various heterocycles, including morpholines, piperidines, piperazines, and piperazinones, are accessible by this method.
