1361938-74-0

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 23165-29-9 3,5-bistrifluoromethylphenylisothiocyanate 
• 1379661-60-5 benzyl (2R,3R)-3-(tert-butyldimethylsilyloxy)-1-(piperidin-1-yl)butan-2-ylcarbamate 
• 1379661-59-2 C₁₇H₂₆N₂O₃ 
• 1361938-79-5 (2R,3R)-3-((tert-butyldimethylsilyl)oxy)-1-(piperidin-1-yl)butan-2-amine 
• 1361938-77-3 (4R,5R)-tert-butyl 2,2,5-trimethyl-4-(piperidin-1-ylmethyl)oxazolidine-3-carboxylate 

Relevant academic research and scientific papers

Threonine-derived thioureas as bifunctional organocatalysts for enantioselective Michael addition

A series of threonine-derived thioureas were developed through the facile modification of L-threonine chiral scaffold. The enantioselective efficiency were evaluated in the catalytic asymmetric Michael addition of 2-hydroxy-1,4-naphthoquinone to nitroalke

Enantioselective Friedel-Crafts reactions between phenols and N-tosylaldimines catalyzed by a leucine-derived bifunctional catalyst

Enantioselective Friedel-Crafts reactions between phenols and N-tosylaldimines were developed using a bifunctional catalyst readily prepared from l-leucine. The chiral benzylic amine products were obtained in high yields (up to 96% yield) and good to high enantiomeric excesses (up to 95% ee).

From the Feist-Bénary reaction to organocatalytic domino Michael-alkylation reactions: Asymmetric synthesis of 3(2H)-furanones

It all adds up! A modified Feist-Bénary reaction employing a domino Michael-alkylation sequence was designed for the enantioselective synthesis of 3(2H)-furanones. L-Threonine-derived tertiary amine/thiourea catalysts were prepared for the first time; such catalysts promoted the designed domino Michael-alkylation reactions in a highly enantioselective manner (see scheme). Copyright