1379661-59-2

Upstream product

• 161150-55-6 (2R,3R)-2-(benzyloxycarbonyl)amino-1,3-butanediol 
• 19728-63-3 N-benzyloxycarbonyl-L-treonine 
• 114102-50-0 C₁₇H₂₃NO₇ 
• 110-89-4 piperidine 
• 1224962-19-9 (2R,3R)-2-(benzyloxycarbonylamino)-3-hydroxybutyl 4-methylbenzenesulfonate 

Downstream Products

• 1361938-74-0 1-(3,5-bis(trifluoromethyl)phenyl)-3-((2R,3R)-3-((tert-butyldimethylsilyl)oxy)-1-(piperidin-1-yl)butan-2-yl)thiourea 
• 1379661-60-5 benzyl (2R,3R)-3-(tert-butyldimethylsilyloxy)-1-(piperidin-1-yl)butan-2-ylcarbamate 

Relevant academic research and scientific papers

Enantioselective Friedel-Crafts reactions between phenols and N-tosylaldimines catalyzed by a leucine-derived bifunctional catalyst

Enantioselective Friedel-Crafts reactions between phenols and N-tosylaldimines were developed using a bifunctional catalyst readily prepared from l-leucine. The chiral benzylic amine products were obtained in high yields (up to 96% yield) and good to high enantiomeric excesses (up to 95% ee).