1361950-89-1

Upstream product

• 13526-66-4 3-bromo-6-chloro-imidazo[1,2-b]pyridazine 
• 179113-90-7 (3-(trifluoromethoxy)phenyl)boronic acid 
• 928337-00-2 6-chloro-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine 
• 20213-86-9 4-amino-2-methylbutan-2-ol hydrogenchloride 

Relevant academic research and scientific papers

Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.

HETEROCYCLIC PROTEIN KINASE INHIBITORS

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.