1361963-67-8Relevant academic research and scientific papers
One-pot synthesis of isoindolinones via three-component Mannich/lactamization cascade reaction
Zhang, Haoyi,Leng, Yixin,Liu, Wenjing,Duan, Wenhu
, p. 1115 - 1127 (2012)
An efficient synthesis of 3-substituted 2,3-dihydroisoindolin-1-ones was achieved with good yields (up to 88%). The process features broad substrate scope, high efficiency, and simplicity, using an one-pot, three-component Mannich/lactamization cascade reaction in the absence or presence of p-toluenesulfonic acid. Copyright Taylor & Francis Group, LLC.
