1361968-52-6 Usage
Appearance
Yellow solid
Molecular weight
325.29 g/mol
Chemical class
Pyridine derivative
Functional groups
Trifluoromethoxy group and propanone moiety
Pharmaceutical industry use
Building block for the synthesis of various organic compounds and drugs
Bioisostere
Trifluoromethoxy group can act as a bioisostere for a methoxy group
Influence on properties
Potentially affects the compound's pharmacokinetic and pharmacodynamic properties
Research interest
Medicinal chemistry and drug development potential
Application
Used by researchers and chemists for its potential applications in the development of new drugs and organic compounds
Check Digit Verification of cas no
The CAS Registry Mumber 1361968-52-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,1,9,6 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1361968-52:
(9*1)+(8*3)+(7*6)+(6*1)+(5*9)+(4*6)+(3*8)+(2*5)+(1*2)=186
186 % 10 = 6
So 1361968-52-6 is a valid CAS Registry Number.
1361968-52-6Relevant academic research and scientific papers
Identification, design and biological evaluation of heterocyclic quinolones targeting plasmodium falciparum Type II NADH:Quinone oxidoreductase (PfNDH2)
Leung, Suet C.,Gibbons, Peter,Amewu, Richard,Nixon, Gemma L.,Pidathala, Chandrakala,Hong, W. David,Pacorel, Bénédicte,Berry, Neil G.,Sharma, Raman,Stocks, Paul A.,Srivastava, Abhishek,Shone, Alison E.,Charoensutthivarakul, Sitthivut,Taylor, Lee,Berger, Olivier,Mbekeani, Alison,Hill, Alasdair,Fisher, Nicholas E.,Warman, Ashley J.,Biagini, Giancarlo A.,Ward, Stephen A.,O'Neill, Paul M.
, p. 1844 - 1857 (2012/05/05)
Following a program undertaken to identify hit compounds against NADH:ubiquinone oxidoreductase (PfNDH2), a novel enzyme target within the malaria parasite Plasmodium falciparum, hit to lead optimization led to identification of CK-2-68, a molecule suitab
