1361982-52-6Relevant academic research and scientific papers
Silanol as a removable directing group for the pdII-catalyzed direct olefination of arenes
Wang, Cong,Ge, Haibo
supporting information; experimental part, p. 14371 - 14374 (2012/01/19)
Need some direction? Silanol was developed as a directing group for the PdII-catalyzed oxidative Heck-type reaction of arenes. A one-pot C-H activation/desilylation process of benzyldiisopropylsilanol was also demonstrated, providing a powerful approach for the synthesis of ortho-alkenyl-substituted alkylarenes (see scheme). Considering the easily attachable and readily removable properties of the silanol group, this reaction will find broad synthetic applications.
