1361988-15-9

Basic information

• Product Name: 1-butyl-4-(3,3,3-trifluoroprop-1-ynyl)benzene
• Synonyms: 1-butyl-4-(3,3,3-trifluoroprop-1-ynyl)benzene
• CAS NO: 1361988-15-9
• Molecular Weight: 226.241
• Mol File: 1361988-15-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-butyl-4-(3,3,3-trifluoroprop-1-ynyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-butyl-4-(3,3,3-trifluoroprop-1-ynyl)benzene(1361988-15-9)
• EPA Substance Registry System: 1-butyl-4-(3,3,3-trifluoroprop-1-ynyl)benzene(1361988-15-9)

Safety Data

• Hazardous Substances Data: 1361988-15-9(Hazardous Substances Data)

Upstream product

• 1415023-67-4 potassium ((4-butylphenyl)ethynyl)trifluoroborate 
• 2926-29-6 Langlois reagent 
• 79887-09-5 (4-butylphenyl)acetylene 
• 887144-97-0 Togni's reagent 

Relevant articles and documents

Copper-mediated trifluoromethylation of potassium alkynyltrifluoroborates with Langlois' reagent Dedicated to Professor Pierre Vogel on the occasion of his 70th birthday

Synthesis of trifluoromethylated acetylenes by copper-mediated trifluoromethylation of potassium alkynyltrifluoroborates with CF3 radicals generated from NaSO2CF3 and tert-butyl hydroperoxide (TBHP) is communicated. The trifluoromethylated acetylenes were obtained in good to moderate yields. The presented method tolerates a wide range of aromatic, heteroaromatic, and aliphatic potassium alkynyltrifluoroborates.

Mild copper-catalyzed trifluoromethylation of terminal alkynes using an electrophilic trifluoromethylating reagent

A catalytic process for trifluoromethylation of terminal alkynes with Togni's reagent has been developed, affording trifluoromethylated acetylenes in good to excellent yields. The reaction is conducted at room temperature and exhibits tolerance to a range