1362047-66-2

Upstream product

• 4119-18-0 2,2-dimethyl-6-(4-methylphenylsulfonyloxymethyl)-5-(4-methylphenylsulfonyloxymethyl)-(3aR,5R,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxole 
• 532-20-7 D-xylofuranose 
• 100-39-0 benzyl bromide 
• 1365475-47-3 C₇H₁₁N₃O₄ 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 89860-19-5 (1R,2R,5R)-2-(dimethoxymethyl)-3,6-dioxabicyclo[3.1.0]hexane 
• 136024-94-7 (2R,3R,4S)-4-azido-2-dimethoxymethyl-3-hydroxytetrahydrofuran 

Downstream Products

• 876917-12-3 (2R,3S,4S)-4-azido-3-benzyloxytetrahydrofuran-2-carbaldehyde 

Relevant academic research and scientific papers

An efficient and convenient formal synthesis of Jaspine B from d-xylose

A formal synthesis of Jaspine B was completed in 42.4% overall yield with only three purification steps (one by crystallization and two by column chromatography). The key step in the synthesis involves a regio- and stereoselective epoxide ring-opening reaction and the configuration inversion of the C3-hydroxyl group through oxidation and reduction. All of the reagents and materials used were quite common and inexpensive.