1362100-28-4

Basic information

• Product Name: (+/-)-(1-allyl-1H-tetrazol-5-yl)(3-methoxyphenyl)(phenyl)methanol
• Synonyms: (+/-)-(1-allyl-1H-tetrazol-5-yl)(3-methoxyphenyl)(phenyl)methanol
• CAS NO: 1362100-28-4
• Molecular Weight: 322.367
• Mol File: 1362100-28-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-(1-allyl-1H-tetrazol-5-yl)(3-methoxyphenyl)(phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-(1-allyl-1H-tetrazol-5-yl)(3-methoxyphenyl)(phenyl)methanol(1362100-28-4)
• EPA Substance Registry System: (+/-)-(1-allyl-1H-tetrazol-5-yl)(3-methoxyphenyl)(phenyl)methanol(1362100-28-4)

Safety Data

• Hazardous Substances Data: 1362100-28-4(Hazardous Substances Data)

Upstream product

• 591-31-1 3-methoxy-benzaldehyde 
• 134172-65-9 m-methoxybenzhydrol 
• 108-86-1 bromobenzene 
• 76457-32-4 1-N-allyltetrazole 
• 6136-67-0 3-methoxybenzophenone 

Downstream Products

• 1362100-51-3 (+/-)-(3-methoxy-phenyl)(phenyl)(1H-tetrazol-5-yl)methanol 
• 37696-01-8 1-methoxy-3-(phenylethynyl)benzene 

Relevant articles and documents

Dehydrative fragmentation of 5-hydroxyalkyl-1 h -tetrazoles: A mild route to alkylidenecarbenes

The development of a mild, base-free method for the generation of alkylidenecarbenes is reported. Treatment of 5-hydroxyalkyl-1H-tetrazoles with carbodiimides generates products arising from the 1,2-rearrangement or [1,5]-C-H bond insertion of a putative alkylidenecarbene. Formation of this divalent intermediate is proposed to occur by way of a tetraazafulvene, which undergoes extrusion of 2 mol of dinitrogen. Details of this methodology, its application to the synthesis of combretastatin A-4, and an improved route to 5-hydroxyalkyl-1H-tetrazoles are described.