136229-99-7Relevant academic research and scientific papers
Synthesis of some new 1-hydroxypyrazole-2-oxides and heterocyclic oximes
Fadda, A. A.
, p. 749 - 753 (2007/10/02)
α,β-Unsaturated oximes (Ia-c) are converted into 1-hydroxypyrazole-2-oxides (IIIa-c) and isoxazole (IV) by reaction with n-butyl nitrite and metal ions in pyridine.Reduction of IIIc with zinc in acetic acid furnishes the pyrazole V.However, reduction of IIIc with sodium dithionite yields the 1-hydroxypyrazole (VI).Acylation of IIIc affords the acyl derivative (VII).Reaction of hydroxylamine hydrochloride and benzaldehyde with oximes VIIIa,b and IXa,b affords O-methyloximinoisoxazoles (Xa,b).
