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2-(4'-aminobenzyl)imidazoline is an organic compound with the molecular formula C10H12N4. It is a derivative of imidazoline, a heterocyclic amine with a five-membered ring containing two nitrogen atoms. The compound features a benzyl group attached to the imidazoline ring through an amino group, which is connected to the 4-position of the benzene ring. This structure endows the molecule with unique chemical and biological properties, making it a subject of interest in various fields, including pharmaceuticals and materials science. Its potential applications may involve the development of new drugs, as well as its use as a building block in the synthesis of more complex molecules.

13623-47-7

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13623-47-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 13623-47-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,6,2 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13623-47:
(7*1)+(6*3)+(5*6)+(4*2)+(3*3)+(2*4)+(1*7)=87
87 % 10 = 7
So 13623-47-7 is a valid CAS Registry Number.

13623-47-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(4,5-dihydro-1H-imidazol-2-ylmethyl)aniline

1.2 Other means of identification

Product number -
Other names 2-ABI

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13623-47-7 SDS

13623-47-7Relevant academic research and scientific papers

Benzylimidazolines as h5-HT(1B/1D) serotonin receptor ligands: A structure-affinity investigation

Law, Ho,Dukat, Malgorzata,Teitler, Milt,Lee, David K. H.,Mazzocco, Lucia,Kamboj, Raj,Rampersad, Vik,Prisinzano, Thomas,Glennon, Richard A.

, p. 2243 - 2251 (2007/10/03)

Benzylimidazolines may represent a class of 5-HT(1D) ligands that has yet to be exploited. On the basis of a previous report that the 2- (substituted-benzyl)imidazoline α-adrenergic agonist oxymetazoline (8) binds with high affinity at calf brain 5-HT(1D) receptors, we explored the structure-affinity relationships of a series of related derivatives. Each of the aromatic substituents was removed and then reinstated in a systematic manner to determine the influence of the individual substituents on binding. It was found that all of the aromatic substituents of 8 act in concert to impart high affinity. However, although the 3-hydroxy group could be removed without significantly reducing affinity for h5-HT(1D) (i.e., human 5- HT(1Dα)) receptors, this modification reduced h5-HT(1B) (i.e., human 5- HT(1Dβ)) receptor affinity by nearly 50-fold. The 2,6-dimethyl groups also contribute to binding but seem to play a greater role for h5-HT(1B) binding than h5-HT(1D) binding. With the appropriate structural modifications, several compounds were identified that display 20- to > 100-fold selectivity for h5-HT(1D) versus h5-HT(1B) receptors. Preliminary functional data suggest that these compounds behave as agonists. Given that 5-HT(1D) agonists are currently being explored for their antimigraine action and that activation of h5-HT(1B) receptors might be associated with cardiovascular side effects, h5- HT(1D)selective agents may offer a new lead for the development of therapeutically efficacious agents.

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