1362664-31-0

Upstream product

• 108-30-5 succinic acid anhydride 
• 125515-31-3 N-{1-[(2R,6)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}benzamide 

Relevant academic research and scientific papers

Morpholino oligonucleotide manufacturing method

Provided is a method capable of manufacturing morpholino oligonucleotides efficiently and with high yields in a liquid phase synthesis method by using, as starting material, a morpholino nucleotide in which the 5'-position hydroxyl group or a hydroxyl group present on a substituent of the 5'-position hydroxyl group has been protected with a protecting group having a C10-30 alkyl group and/or a C10-300 alkenyl group.

Morpholino Nucleic Acid Derivatives

The present invention provides a useful morpholino nucleic acid derivative for synthesizing a morpholino nucleic acid oligomer. The present invention provides a compound represented by the following general formula (1) or a salt thereof. Here, R1 /s