136309-04-1 Usage
Uses
Used in Food Industry:
2-Cyano-6-methylpyrazine is used as a flavor additive for its characteristic earthy and roasted aroma, which is commonly found in roasted coffee and cocoa. It enhances the taste and aroma profile of these products, contributing to a richer sensory experience for consumers.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-Cyano-6-methylpyrazine is utilized in the synthesis of various drugs. Its unique chemical properties make it a valuable intermediate in the development of new pharmaceutical compounds, potentially leading to innovative treatments and therapies.
Used in Agrochemical Production:
2-Cyano-6-methylpyrazine also finds application in the agrochemical sector, where it is used in the production of various agrochemicals. Its role in this industry is crucial for the development of effective and safe products for agricultural use, such as pesticides and fertilizers.
Safety and Regulation:
Considering its use in food and other industries, 2-Cyano-6-methylpyrazine is considered safe for consumption in small quantities. Food safety authorities regulate its use to ensure that it meets safety standards and does not pose any health risks to consumers. This regulation helps maintain the balance between the benefits of its use and the need to protect public health.
Check Digit Verification of cas no
The CAS Registry Mumber 136309-04-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,3,0 and 9 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 136309-04:
(8*1)+(7*3)+(6*6)+(5*3)+(4*0)+(3*9)+(2*0)+(1*4)=111
111 % 10 = 1
So 136309-04-1 is a valid CAS Registry Number.
136309-04-1Relevant academic research and scientific papers
Studies on Pyrazines. Part 22. Lewis Acid-Mediated Cyanation of Pyrazine N-Oxides with Trimethylsilyl Cyanide: New Route to 2-Substituted 3-Cyanopyrazines
Sato, Nobuhiro,Shimomura, Yuji,Ohwaki, Yoshie,Takeuchi, Ryo
, p. 2877 - 2882 (2007/10/02)
Reaction of 3-substituted pyrazine 1-oxides with trimethylsilyl cyanide in the presence of triethylamine in acetonitrile gave the corresponding cyanopyrazines, yields of which depended remarkably on the substituent.Electron-donating groups enhanced the cyanation with high regioselectivity to 2-substituted 3-cyanopyrazines, while a chloro substituent suppressed the conversion.Addition of zinc halide to the reaction mixture, in most cases, increased the reactivity and improved the regioselectivity.On the other hand, the N-oxides carrying an electron-withdrawing methoxycarbonyl or N-butylcarbamoyl group underwent the cyanation, without need for the Lewis acid, to provide a mixture of nearly equal amounts of 2-substituted 3- and 5-cyanopyrazines.The latter compound was exclusively obtained when 3-methoxycarbonyl- or 3-cyanopyrazine 1-oxide was treated with diethoxyphosphoryl cyanide.
