136309-07-4 Usage
Uses
Used in Pharmaceutical Industry:
6-Methoxy-pyrazine-2-carbonitrile is used as a building block for the synthesis of specialized pharmaceuticals due to its unique chemical structure and properties.
Used in Agrochemical Industry:
6-Methoxy-pyrazine-2-carbonitrile is used as a building block for the production of pesticides, leveraging its specific chemical characteristics to create effective agrochemicals.
Used in Material Development:
6-Methoxy-pyrazine-2-carbonitrile may be utilized in the development of new materials, given its unique chemical properties that could contribute to innovative material compositions.
Used in Chemical Process Development:
6-Methoxy-pyrazine-2-carbonitrile may also have potential applications in the development of new chemical processes, where its specific attributes can be harnessed to improve or create novel chemical methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 136309-07-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,3,0 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 136309-07:
(8*1)+(7*3)+(6*6)+(5*3)+(4*0)+(3*9)+(2*0)+(1*7)=114
114 % 10 = 4
So 136309-07-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H5N3O/c1-10-6-4-8-3-5(2-7)9-6/h3-4H,1H3
136309-07-4Relevant academic research and scientific papers
Studies on Pyrazines. Part 22. Lewis Acid-Mediated Cyanation of Pyrazine N-Oxides with Trimethylsilyl Cyanide: New Route to 2-Substituted 3-Cyanopyrazines
Sato, Nobuhiro,Shimomura, Yuji,Ohwaki, Yoshie,Takeuchi, Ryo
, p. 2877 - 2882 (2007/10/02)
Reaction of 3-substituted pyrazine 1-oxides with trimethylsilyl cyanide in the presence of triethylamine in acetonitrile gave the corresponding cyanopyrazines, yields of which depended remarkably on the substituent.Electron-donating groups enhanced the cyanation with high regioselectivity to 2-substituted 3-cyanopyrazines, while a chloro substituent suppressed the conversion.Addition of zinc halide to the reaction mixture, in most cases, increased the reactivity and improved the regioselectivity.On the other hand, the N-oxides carrying an electron-withdrawing methoxycarbonyl or N-butylcarbamoyl group underwent the cyanation, without need for the Lewis acid, to provide a mixture of nearly equal amounts of 2-substituted 3- and 5-cyanopyrazines.The latter compound was exclusively obtained when 3-methoxycarbonyl- or 3-cyanopyrazine 1-oxide was treated with diethoxyphosphoryl cyanide.
