136320-11-1

Basic information

• Product Name: 4-amino-5-(1-hydroxyethyl)-6-phenylpyridazin-3(2H)-one
• Synonyms: 4-amino-5-(1-hydroxyethyl)-6-phenylpyridazin-3(2H)-one
• CAS NO: 136320-11-1
• Molecular Weight: 231.254
• Mol File: 136320-11-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-amino-5-(1-hydroxyethyl)-6-phenylpyridazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-5-(1-hydroxyethyl)-6-phenylpyridazin-3(2H)-one(136320-11-1)
• EPA Substance Registry System: 4-amino-5-(1-hydroxyethyl)-6-phenylpyridazin-3(2H)-one(136320-11-1)

Safety Data

• Hazardous Substances Data: 136320-11-1(Hazardous Substances Data)

Upstream product

• 17335-08-9 5-acetyl-4-aminopyridazinone 
• 17334-68-8 3-methyl-4-phenylisoxazolo[3,4-d]pyridazin-7(6H)-one 

Relevant articles and documents

4-Amino-5-vinyl-3(2H)-pyridazinones and analogues as potent antinociceptive agents: Synthesis, SARs, and preliminary studies on the mechanism of action

A series of 4-amino-5-vinyl-3(2H)-pyridazinones and analogues were synthesized and their antinociceptive effect was evaluated in the mouse abdominal constriction model. Several of the novel compounds showed ED50 values in the range 6-20 mg/kg/s

REDUCTIVE CLEAVAGE OF ISOXAZOLOPYRIDAZINONES: A SYNTHETIC APPROACH TO VARIOUS 4,5-FUNCTIONALIZED 3(2H)-PYRIDAZINONES

4-Aminopyridazin-3(2H)-ones substituted at position 5 with a variety of oxygenated carbon chains were obtained in good yields by reductive opening of the pentatomic ring of isoxazolopyridazinones (1).Starting from ethyl 4-acylisoxazole-3-carboxylat