1363378-75-9Relevant academic research and scientific papers
Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors α/γ dual agonists
Fracchiolla, Giuseppe,Laghezza, Antonio,Piemontese, Luca,Parente, Mariagiovanna,Lavecchia, Antonio,Pochetti, Giorgio,Montanari, Roberta,Giovanni, Carmen Di,Carbonara, Giuseppe,Tortorella, Paolo,Novellino, Ettore,Loiodice, Fulvio
, p. 2141 - 2151 (2012)
PPARs are transcription factors that govern lipid and glucose homeostasis and play a central role in cardiovascular disease, obesity, and diabetes. Thus, there is significant interest in developing new agonists for these receptors. Given that the introduc
