1363381-20-7 Usage
Uses
Used in Pharmaceutical Industry:
Tert-butyl 7-oxo-5-oxa-2,8-diazaspiro[3.5]nonane-2-carboxylate is used as a reactant for the efficient preparation of a diverse array of amino alcohol chiral fragments. These chiral fragments are essential building blocks in the synthesis of various pharmaceutical compounds, particularly those with chiral centers that are crucial for their biological activity and selectivity.
Used in Chemical Synthesis:
In the field of chemical synthesis, tert-butyl 7-oxo-5-oxa-2,8-diazaspiro[3.5]nonane-2-carboxylate serves as a versatile intermediate for the creation of complex organic molecules. Its unique structure allows for multiple points of reactivity, making it a valuable component in the synthesis of a wide range of compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
Due to its structural complexity and reactivity, tert-butyl 7-oxo-5-oxa-2,8-diazaspiro[3.5]nonane-2-carboxylate is also utilized in research and development settings. It can be employed as a test compound to study various reaction mechanisms, explore new synthetic routes, and develop innovative methodologies in organic chemistry. This contributes to the advancement of scientific knowledge and the discovery of new chemical processes and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1363381-20-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,3,3,8 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1363381-20:
(9*1)+(8*3)+(7*6)+(6*3)+(5*3)+(4*8)+(3*1)+(2*2)+(1*0)=147
147 % 10 = 7
So 1363381-20-7 is a valid CAS Registry Number.
1363381-20-7Relevant academic research and scientific papers
QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS
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, (2020/04/25)
The present application relates to novel quinazoline compounds as inhibitors of type I receptor tyrosine kinases, the pharmaceutical compositions comprising one or more of the compounds and salts thereof as an active ingredient, and the use of the compounds and salts thereof in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals and especially in humans.
Efficient Routes to a Diverse Array of Amino Alcohol-Derived Chiral Fragments
Haftchenary, Sina,Nelson, Shawn D.,Furst, Laura,Dandapani, Sivaraman,Ferrara, Steven J.,Bo?kovi?, ?arko V.,Figueroa Lazú, Samuel,Guerrero, Adrian M.,Serrano, Juan C.,Crews, Demarcus K.,Brackeen, Cristina,Mowat, Jeffrey,Brumby, Thomas,Bauser, Marcus,Schreiber, Stuart L.,Phillips, Andrew J.
supporting information, p. 569 - 574 (2016/10/06)
Efficient syntheses of chiral fragments derived from chiral amino alcohols are described. Several unique scaffolds were readily accessed in 1-5 synthetic steps leading to 45 chiral fragments, including oxazolidinones, morpholinones, lactams, and sultams. These fragments have molecular weights ranging from 100 to 255 Da and are soluble in water (0.085 to >15 mM).
