1008526-71-3Relevant academic research and scientific papers
PYRAZINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS
-
Paragraph 0193; 0195, (2020/12/25)
Pyridine carbamates, pharmaceutical compositions containing pyridine carbamates, and uses of the pyridine carbamates and pharmaceutical compositions for modulating GluN2B receptors and for treating diseases, disorders, and medical conditions mediated by GluN2B receptor activity.
PYRAZINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS
-
Page/Page column 45-46, (2020/12/30)
Pyridine carbamates, pharmaceutical compositions containing pyridine carbamates, and uses of the pyridine carbamates and pharmaceutical compositions for modulating GluN2B receptors and for treating diseases, disorders, and medical conditions mediated by GluN2B receptor activity.
QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS
-
Page/Page column 145, (2020/04/25)
The present application relates to novel quinazoline compounds as inhibitors of type I receptor tyrosine kinases, the pharmaceutical compositions comprising one or more of the compounds and salts thereof as an active ingredient, and the use of the compounds and salts thereof in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals and especially in humans.
QUINAZOLINE COMPOUND FOR EGFR INHIBITION
-
Paragraph 0210; 0212, (2019/11/21)
Disclosed is a novel quinazoline compound. Specifically, disclosed are a compound represented by the formula (I) and a pharmacologically acceptable salt.
THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS
-
Page/Page column 29-30, (2009/03/07)
A series of thieno[2,3-b]pyridine derivatives which are substituted in the 2- position by a substituted anilino moiety, being selective inhibitors of human MEK (MAPKK) enzymes, are accordingly of benefit in medicine, for example in the treatment, of inflammatory, autoimmune, cardiovascular, proliferative (including oncological) and nociceptive conditions.
FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS
-
Page/Page column 45, (2008/06/13)
A series of 4,5,6,7-tetrahydrothieno[2,3-c]azepin-8-one derivatives, and analogues thereof, which are substituted in the 2-position by a substituted anilino moiety, being selective inhibitors of human MEK (MAPKK) enzymes, are accordingly of benefit in med
