1363381-75-2Relevant academic research and scientific papers
DUAL KINASE-BROMODOMAIN INHIBITORS
-
, (2021/12/12)
Provided herein are compounds of Formula (I) that are dual inhibitors of kinases and bromo-domain proteins. The disclosure also relates to pharmaceutical compositions containing such compounds, methods for using such compounds in the treatment of cancers, particularly, the treatment of multiple myeloma cancers, and to related uses.
PYRROLE [2, 1-F][1, 2, 4]TRIAZINE DERIVATIVE AND ANTITUMOR EFFECT THEREOF
-
, (2015/04/15)
Disclosed are a pyrrolo[2,1-f][1,2,4]triazine derivative of Formula (I) and use thereof for treating tumors. The compound has remarkable antiproliferative activity for a variety of human tumor cell lines, and is useful for treating cancers, and especially solid tumors such as gastric cancer, lung cancer, liver cancer, breast cancer, colon cancer, prostatic cancer, and oral cancer.
