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Diethyl 1H-pyrrole-2,4-dicarboxylate is a chemical compound with the molecular formula C10H13NO4. It is an ester derivative of pyrrole-2,4-dicarboxylic acid, featuring a pyrrole ring structure with two carboxylate groups. Known for its mild, fruity odor, this colorless to light yellow liquid is slightly soluble in water and highly soluble in organic solvents. It serves as a key intermediate in the synthesis of bioactive compounds, making it a valuable building block in the production of various pharmaceuticals and agrochemicals.

55942-40-0

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55942-40-0 Usage

Uses

Used in Pharmaceutical Industry:
Diethyl 1H-pyrrole-2,4-dicarboxylate is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of bioactive compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, Diethyl 1H-pyrrole-2,4-dicarboxylate is utilized as a building block for the production of agrochemicals. Its versatility in organic synthesis enables the creation of compounds with pesticidal or herbicidal properties, contributing to crop protection and yield enhancement.
Used in Organic Synthesis:
Diethyl 1H-pyrrole-2,4-dicarboxylate is employed as a versatile building block in organic synthesis. Its pyrrole ring structure and carboxylate groups facilitate the formation of a wide range of chemical compounds, making it a valuable component in the development of new materials and molecules with diverse applications.

Check Digit Verification of cas no

The CAS Registry Mumber 55942-40-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,9,4 and 2 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 55942-40:
(7*5)+(6*5)+(5*9)+(4*4)+(3*2)+(2*4)+(1*0)=140
140 % 10 = 0
So 55942-40-0 is a valid CAS Registry Number.

55942-40-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Diethyl 1H-pyrrole-2,4-dicarboxylate

1.2 Other means of identification

Product number -
Other names Pyrrol-2,4-dicarbonsaeure-diaethylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55942-40-0 SDS

55942-40-0Relevant articles and documents

2,7,12,17-Tetra(2,5-thienylene)-substituted porphycenes

Kuzuhara, Daiki,Nakaoka, Haruka,Matsuo, Kyohei,Aratani, Naoki,Yamada, Hiroko

, p. 898 - 907 (2019)

We report syntheses of thiophene and dithiophene-substituted porphycenes (ThPc and DThPc) at 2,7,12,17-positions by McMurry coupling. The crystal structure of ThPc revealed that the porphycene plane shows a highly planar structure, and the dihedral angles between the porphycene core and thiophene are relatively small at 21deg and 18deg. ThPc and DThPc exhibit red-shifted and broadened absorption because of the extension of I conjugations through porphycene to the substituted thiophenes. We found that introduction of thiophene units onto porphycene results in decreasing the HOMO-LUMO differences effectively.

A CONVERGENT SYNTHESIS OF SUBSTITUTED PYRROLIDINES BY 1,3 DIPOLAR CYCLOADDITION

Kraus, George A.,Nagy, Jon O.

, p. 2727 - 2730 (1981)

Thiazolium ylids 2a and 2b are converted to 4 in 3 steps.

ROCK INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF

-

Page/Page column 42, (2022/01/24)

The invention relates to a ROCK inhibitor represented by formula (I), its preparation method and its use. The ROCK inhibitor has excellent ROCK inhibition activity, in particular good selective inhibition on ROCK2 kinase, has good safety and metabolic stability, and has high bioavailability. The process of preparing the ROCK inhibitor is simple, and the ROCK inhibitor is easy to purify, and therefore offers good prospects for application.

SUBSTITUTED PYRAZINE CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN EP3 RECEPTOR ANTAGONISTS

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Page/Page column 60, (2021/05/21)

The invention relates to substituted pyrazine carboxamide derivatives of formula (I) and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/ or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.

SUBSTITUTED PYRROLO TRIAZINE CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN EP3 RECEPTOR ANTAGONISTS

-

Page/Page column 65, (2021/05/21)

The invention relates to substituted pyrrole triazine carboxamide derivatives of formula (I) and to processes for their preparation, and also /to their use for preparing medicaments for the treatment and/ or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.

DUAL KINASE-BROMODOMAIN INHIBITORS

-

Page/Page column 101; 197, (2021/12/12)

Provided herein are compounds of Formula (I) that are dual inhibitors of kinases and bromo-domain proteins. The disclosure also relates to pharmaceutical compositions containing such compounds, methods for using such compounds in the treatment of cancers, particularly, the treatment of multiple myeloma cancers, and to related uses.

Histone deacetylase inhibitors derived from 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine and related heterocycles selective for the HDAC6 isoform

Blackburn, Christopher,Barrett, Cynthia,Brunson, Mable,Chin, Janice,England, Dylan,Garcia, Kris,Gigstad, Kenneth,Gould, Alexandra,Gutierrez, Juan,Hoar, Kara,Rowland, R. Scott,Tsu, Christopher,Ringeling, John,Wager, Krista,Xu, He

, p. 5450 - 5454 (2015/01/08)

Acyl derivatives of 4-(aminomethyl)-N-hydroxybenzamide are potent sub-type selective HDAC6 inhibitors. Constrained heterocyclic analogs based on 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine show further enhanced HDAC6 selectivity and inhibitory activity in ce

PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES

-

Page/Page column 68-69, (2012/10/07)

Disclosed are compounds of formula (I) and pharmaceutically acceptable salts thereof. The compounds of formula (I) inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

TRICYCLOPYRAZOLE DERIVATIVES

-

, (2011/06/25)

Compounds which are tricyclopyrazole derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/o

SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF

-

Page/Page column 54-55, (2011/10/19)

This invention provides compounds of formula (I): wherein X1, X2, R1a, R1b, R1c, R1d, n, and G have values as described in the specification, useful as inhibitors of HDAC6. The invention al

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