1363389-10-9Relevant academic research and scientific papers
Synthesis, characterization and antihypertensive activity of some new substituted pyridazine derivatives
Mishra, Ravinesh,Siddiqui, Anees A.,Husain, Asif,Rashid, Mohd,Prakash, Atish,Tailang, Mukul,Kumar, Muneesh,Srivastava, Neeti
, p. 856 - 859 (2012/05/05)
Some new 6-(substituted phenyl)-2-(4-substituted phenyl-5-thioxo-4,5- dihydro-1H-1,2,4-triazol-3-yl)-4,5-dihydropyridazin-3(2H)-one derivatives were synthesized by a sequence of reactions starting from respective aryl hydrocarbons. The final compounds (4a-i) were screened for antihypertensive activities by non-invasive method using Tail Cuff method. The compounds 4e and 4i showed appreciable antihypertensive activity.
