1363411-75-9Relevant academic research and scientific papers
The p-toluenesulfonic acid-catalyzed transformation of polyfluorinated 2-alkynylanilines to 2-aminoarylketones and indoles
Politanskaya, Larisa,Shteingarts, Vitalij,Tretyakov, Evgeny,Potapov, Alexander
supporting information, p. 5328 - 5332 (2015/09/01)
The reactivity of a series of polyfluorinated 2-alkynylanilines with various alcohols using p-TSA has been studied. It was found that hydration of the triple bond gave rise to polyfluorinated 2-aminoarylketones and competed with an electrophilic heterocyc
Synthesis of indoles with a polyfluorinated benzene ring
Politanskaya, Larisa V.,Chuikov, Igor P.,Shteingarts, Vitalij D.
, p. 8477 - 8486 (2013/09/02)
A two-step sequence consisting of a Sonogashira coupling of polyfluorinated 2-iodoanilines with terminal alkynes, followed by a KOH promoted cyclization of the 2-alkynylanilines thus formed, has been developed as a one-pot synthesis of 2-R-indoles (R=n-Bu
Synthesis of polyfluorinated ortho-alkynylanilines
Politanskaya, Larisa V.,Chuikov, Igor P.,Kolodina, Ekaterina A.,Shvartsberg, Mark S.,Shteingarts, Vitalij D.
, p. 97 - 107 (2012/03/27)
A series of polyfluorinated ortho-alkynylanilines - the versatile building blocks for diverse polyfluorobenzo azaheterocycles - have been synthesized by the Sonogashira reaction of polyfluorinated ortho-iodanilines with terminal alkynes.
