136347-48-3

Upstream product

• 24461-40-3 1-(1-propenyl)piperidine 
• 3296-02-4 p-azidofluorobenzene 
• 7182-09-4 N-(1-propenyl)piperidine 

Downstream Products

• 1374672-54-4 6-[3-(4-fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-nicotinic acid methyl ester 
• 1374672-55-5 6-[3-(4-Fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-N-(tetrahydro-pyran-4-yl)-nicotinamide 
• 1374672-67-9 3-chloro-6-[3-(4-fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-pyridazine 
• 1374672-73-7 6-((1-(4-Fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)methoxy)-2-isopropyl-1H-pyrrolo[3,4-c]pyridin-3(2H)-one 
• 1374672-74-8 5-[3-(4-Fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-pyrazine-2-carboxylic acid (tetrahydro-pyran-4-yl)-amide 
• 1374673-23-0 6-[3-(4-fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-nicotinic acid 
• 1374673-30-9 5-[3-(4-Fluoro-phenyl)-5-methyl-3H-[1,2,3]-triazol-4-ylmethoxy]-pyrazine-2-carboxylic acid methyl ester 
• 1374673-31-0 5-[3-(4-fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-pyrazine-2-carboxylic acid 
• 1374645-54-1 5-[3-(4-Fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid (tetrahydro-pyran-4-yl)-amide 
• 1374645-70-1 5-[3-(4-fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester 
• 1374645-71-2 5-[3-(4-Fluoro-phenyl)-5-methyl-3H-[1,2,3]-triazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid 
• 1380689-21-3 6-(4-(1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)-1H-imidazol-1-yl)nicotinic acid 
• 1380689-16-6 1-(4-Fluoro-phenyl)-5-(1H-imidazol-4-yl)-4-methyl-1H-[1,2,3,]triazole 
• 1380689-15-5 2-bromo-1-[3-(4-fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-yl]-ethanone 

Relevant academic research and scientific papers

NOVEL TRIAZOLE COMPOUNDS II

The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, u, v, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts thereof. The compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as pharmaceuticals.

NOVEL TRIAZOLE COMPOUNDS I

The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.

TRIAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS

The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, u,v, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts thereof. The active compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.

TRIAZOLE DERIVATIVES AND THEIR USE FOR NEUROLOGICAL DISORDERS

The present invention is concerned with novel triazole compounds of formula (I) wherein A, X, Y, Z, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of present invention have affinity and selectivity for the GABA A α5 receptor. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments.

NOVEL TRIAZOLE COMPOUNDS III

The present invention is concerned with novel 1,2,3-triazole-imidazole compounds of formula (I) wherein X, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active

1,2,3-TRIAZOLE-IMIDAZOLECOMPOUNDS

The present invention is concerned with novel 1,2,3-triazole-imidazole compounds of formula (I) wherein X, R1, R2, and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active

1,2,3-Triazole derivatives active as inhibitors of the enzyme HMG-COA reductase and pharmaceutical compositions containing them

Compounds of formulawherein R, R1, R2, R3, and Z have the meanings reported in the specification,and intermediates for their preparation are described. The compounds of formula I have antiatherosclerotic activity as inhibitors of the enzyme HMG-CoA reductase and they are useful in the pharmaceutical field. Compositions for pharmaceutical use containing a compound of formula I as active ingredient are described too.