1363649-60-8Relevant articles and documents
Synthesis of pyrido[1,2- a ]indole malonates and amines through aryne annulation
Rogness, Donald C.,Markina, Nataliya A.,Waldo, Jesse P.,Larock, Richard C.
experimental part, p. 2743 - 2755 (2012/05/05)
Pyrido[1,2-a]indoles are known as medicinally and pharmaceutically important compounds, but there is a lack of efficient methods for their synthesis. We report a convenient and efficient route to these privileged structures starting from easily accessible 2-substituted pyridines and aryne precursors. A small library of compounds has been synthesized utilizing the developed method, affording variously substituted pyrido[1,2-a]indoles in moderate to good yields.
