136376-30-2Relevant academic research and scientific papers
Chemoenzymatic Synthesis of Carbocyclic Oxetanocin-A Involving a Novel Photochemical Rearrangement
Cotterill, Ian C.,Roberts, Stanley M.
, p. 2585 - 2586 (2007/10/02)
The anti-herpes agent carbocyclic oxetanocin-A (-)-2 has been prepared from the bicyclic ketone 3 via resolution of the bromohydrin 4 (using an enzyme-catalysed trans-esterification reaction) and a photocatalysed rearrangement of the epoxide (+)-6 to the
Enzymatic Resolution of Sterically Demanding Bicycloheptanes: Evidence for a Novel Hydrolase in Crude Porcine Pancreatic Lipase and the Advantages of using Organic Media for Some of the Biotransformations
Cotterill, Ian C.,Sutherland, Alan G.,Roberts, Stanley M.,Grobbauer, Robert,Spreitz, Josef,Faber, Kurt
, p. 1365 - 1368 (2007/10/02)
Sterically demanding 7,7-dimethylbicyclohept-2-en-6-one 1 was enzymatically resolved via the exo-acetate 11a using crude porcine pancreatic lipase.By employing different fractions of hydrolases from the crude enzyme, evidence was obtained that an e
