1363913-43-2Relevant academic research and scientific papers
TOPP: A novel nitroxide-labeled amino acid for EPR distance measurements
Stoller, Sven,Sicoli, Giuseppe,Baranova, Tatiana Y.,Bennati, Marina,Diederichsen, Ulf
, p. 9743 - 9746 (2011/11/29)
A new tool: The amino acid 4-(3,3,5,5-tetramethyl-2,6-dioxo-4- oxylpiperazin-1-yl)-L-phenylglycine (TOPP), which has a rigid nitroxide spin label, can be used for EPR-based distance measurements in peptides. The key feature of the design is the defined orientation of the nitroxide in space with respect to the peptide backbone. EPR measurements provide evidence for the low conformational flexibility of the TOPP label. Copyright
