136401-04-2Relevant articles and documents
POLYBROMINATED AROMATIC COMPOUNDS V. REACTION OF PENTABROMOTOLUENE WITH SODIUM METHOXIDE IN PYRIDINE
Shishkin, V. N.,Lapin, K. K.,Tanaseichuk, B. S.,Butin, K. P.
, p. 1882 - 1887 (2007/10/02)
During the reaction of pentabromotoluene with sodium methoxide in pyridine, together with the products from methoxydebromination and protodebromination, the products from substitution of both the bromine atom in the aromatic ring and hydrogen atom in the methyl group by methoxy groups are formed.The directing effect of the methyl and methoxymethyl groups during substitution of the bromine in the pentabromophenyl ring by the methoxide ion was studied, and it was shown that the directing selectivity of these substituents is low.The methyl group is predominantly a meta-orientant, whereas the methoxymethyl group is predominantly a para-orientant.