1364054-79-4Relevant academic research and scientific papers
Trinuclear non-heme iron complexes based on 4-substituted 2,6-diacylpyridine ligands as catalysts in aerobic allylic oxidations
Rabe, Volker,Frey, Wolfgang,Baro, Angelika,Laschat, Sabine
, p. 197 - 210 (2012/04/10)
Taking the regio- and chemoselectivities of our iron complex precursors with pyridine core in aerobic oxidations into account, we envisioned a more effective influence on catalytic properties by the introduction of different substituents in 4-position of the pyridine moiety. The synthesis of these novel 4-substituted (pyridine-2,6-diyl)dipropanoic acids 4 is described. Analogously to the unsubstituted derivative, ligands 4 reacted with Fe(ClO4) 3 to form trinuclear Fe3(μ3-O) complexes 3, which were tested in the aerobic Gif-type oxidation of α-pinene to myrtenol, verbenone, myrtenal, and pinene oxide. The electronic nature of the substituents was found to slightly effect the ratio of allylic oxidation/epoxidation, whereas its influence on the oxidation preference of secondary to primary C-H bonds is negligible as compared to the unsubstituted complex. Copyright
