136409-34-2

Upstream product

• 26740-23-8 N-(1,2-Diphenylvinyl)iminotriphenylphosphoran 
• 4695-13-0 2,2-diphenylacetamide 
• 14447-41-7 (E)-1-bromo-1,2-diphenylethene 
• 119379-68-9 (E)-1,1'-(1-Iodo-1,2-ethenediyl)bisbenzene 
• 156181-20-3 (Z)-1,1'-(1-Iodo-1,2-ethenediyl)bisbenzene 
• 525-06-4 diphenyl ketene 
• 136409-29-5 1,1,4,5-Tetraphenyl-3-(triphenylphosphonio)-3-aza-1,4-pentadien-2-olat 

Downstream Products

• 960117-58-2 2-benzhydryl-4,5-diphenyloxazole 

Relevant academic research and scientific papers

Sequential copper-catalyzed vinylation/ cyclization: An efficient synthesis of functionalized oxazoles

A modular and practical synthesis of highly substituted oxazoles has been developed. The transformation consists of a sequential copper-catalyzed amidation of vinyl halides followed by cyclization promoted by iodine. A wide variety of functionalized oxazo

N-Vinylketenimines

The title compounds 5 are generated in situ from N-vinyliminotriphenylphosphoranes 1 and ketenes 2 in a Wittig-type reaction.The phosphoranes are useful intermediates for the preparation of numerous heterocycles as illustrated by the formation of 1,3-oxazines 8, pyridinones 9, pyrimidinones 10 and 1,3-thiazines 11.Water adds readily to 5 to yield vinylacetamides 7, whereas thermal rearrangement gives rise to the isoquinoline 4 or the spiro system 6, respectively.Under very mild conditions, crystalline precursors (type 3) of the N-vinylketenimines, which still contain the triphenylphosphonio group, have been isolated.These react like the N-vinylketenimines generated in situ, giving however less byproducts. Key Words: Phosphorus ylides / Ketenes / Ketenimines