1364165-93-4Relevant articles and documents
Identification of a novel aminotetralin class of HDAC6 and HDAC8 selective inhibitors
Tang, Guozhi,Wong, Jason C.,Zhang, Weixing,Wang, Zhanguo,Zhang, Nan,Peng, Zhenghong,Zhang, Zhenshan,Rong, Yiping,Li, Shijie,Zhang, Meifang,Yu, Lingjie,Feng, Teng,Zhang, Xiongwen,Wu, Xihan,Wu, Jim Z.,Chen, Li
, p. 8026 - 8034 (2014/12/10)
Herein we report the identification of a novel class of HDAC6 and HDAC8 selective inhibitors through a unique chemistry and phenotypic screening strategy. Tetrahydroisoquinoline 12 was identified as a potent HDAC6 and HDAC8 dual inhibitor from a focused l
