136444-76-3Relevant academic research and scientific papers
First stereoselective total synthesis of an anti-fouling agent, C2-symmetric natural macrolide trichobotryside A
Narala, Siva Ganesh,Nagalatha,Venkat Narsaiah
, p. 495 - 508 (2018)
A stereoselective total synthesis of 16-membered macrodiolide trichobotryside A has been accomplished. The key features are: regioselective epoxide opening, Reetz anti-allylation, Sharpless asymmetric epoxidation, cross metathesis and Yamaguchi protocols
Total Synthesis of Tetraketide and Cryptorigidifoliol i via a Sequential Allylation Strategy
Padhi, Birakishore,Reddy, G. Sudhakar,Mohapatra, Debendra K.
, p. 2788 - 2796 (2016/12/06)
A unified and efficient synthetic route for both tetraketide (1) and cryptorigidifoliol I (2) has been devised successfully from commercially available starting materials in 11 and 17 steps, with 16% and 11% overall yields, respectively. Highlights of the syntheses involved sequential Lewis acid-catalyzed highly regio- and diastereoselective allylations and intramolecular Mitsunobu lactonization.
Total Synthesis of (-)-Colletol
Keck, Gary E.,Murry, Jerry A.
, p. 6606 - 6611 (2007/10/02)
The first total synthesis of the unsymmetrical bis-macrolide (-)-colletol is described.The synthesis involves a Lewis acid mediated addition of triphenylallylstannane to aldehyde 14 to set the C12 stereochemistry.The penultimate step utilized m
