86272-43-7Relevant academic research and scientific papers
Total Synthesis of (-)-Colletol
Keck, Gary E.,Murry, Jerry A.
, p. 6606 - 6611 (1991)
The first total synthesis of the unsymmetrical bis-macrolide (-)-colletol is described.The synthesis involves a Lewis acid mediated addition of triphenylallylstannane to aldehyde 14 to set the C12 stereochemistry.The penultimate step utilized m
A Unified Synthetic Approach to Optically Pure Curvularin-Type Metabolites
Allu, Srinivasa Rao,Banne, Sreenivas,Jiang, Jia,Qi, Na,Guo, Jian,He, Yun
, p. 7227 - 7237 (2019/06/07)
A unified and concise approach to the synthesis of nine curvularin-type metabolites and two analogues has been developed with few steps and high yields. Among them, sumalactones A-D were synthesized for the first time. The key steps in this approach inclu
Total Synthesis of Tetraketide and Cryptorigidifoliol i via a Sequential Allylation Strategy
Padhi, Birakishore,Reddy, G. Sudhakar,Mohapatra, Debendra K.
, p. 2788 - 2796 (2016/12/06)
A unified and efficient synthetic route for both tetraketide (1) and cryptorigidifoliol I (2) has been devised successfully from commercially available starting materials in 11 and 17 steps, with 16% and 11% overall yields, respectively. Highlights of the syntheses involved sequential Lewis acid-catalyzed highly regio- and diastereoselective allylations and intramolecular Mitsunobu lactonization.
CONCERNING THE ROLE OF LEWIS ACIDS IN CHELATION CONTROLLED ADDITION TO CHIRAL ALKOXY ALDEHYDES
Reetz, M. T.,Kesseler, K.,Jung, A.
, p. 729 - 732 (2007/10/02)
Chiral α- and β-alkoxy aldehydes react stereoselectively with various C-nucleophiles in th epresence of Lewis acids to provide chelation controlled adducts.
